What basic vaccinations do mixed-breed puppies need?

Core vaccinations every puppy should receive

Puppies require a series of core vaccines to protect them from common, potentially serious diseases. Vaccination schedules vary slightly by region and vet, but the core set consistently includes protection against several key viruses and bacteria.

Typical core vaccines:

• Distemper, Adenovirus (hepatitis) and Parvovirus (often combined as DAPP/DHPP).
• Rabies vaccine as required by local law.

A typical timeline:

• First set at 6–8 weeks: start core series.
• Booster shots every 3–4 weeks until around 16 weeks of age.
• Rabies often given near 12–16 weeks depending on local rules.

Non-core vaccines (given based on lifestyle and exposure risk) may include Bordetella (kennel cough), Leptospirosis, and Lyme disease. Your veterinarian will recommend a schedule tailored to the puppy’s environment, travel plans, and regional disease prevalence. Maintaining proper vaccination and keeping records are essential for social settings like doggy daycare and boarding.